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R&D
activities
In addition
to pharmaceutical formulations, CT laboratories' R&D division,
is focused on the development of original chemical entities targeted
to the treatment of alcohol addiction/abuse and depression/anxiety disorders.
A) CHEMICAL
SYNTHESIS
- Laboratory
scale synthesis.
B) CHEMICAL
DEVELOPMENT
- Study
of chemical structure (NMR, IR, NIR, Elemental Analysis),
- Analytical
development with validation studies.
C) PHARMACOLOGICAL
ACTIVITIES
- Preliminary
pharmacological screening by means of behavioural tests to define neuropharmacological
profile,
- Evaluation
of selected molecules by specific animal models (ethanol intake in rats,
withdrawal syndrome in rats and other species),
- Tests
of receptorial binding (outsourcing),
- Pharmacokinetic
studies in small animals (rats and rabbits),
- Initial
toxicological data (LD50).

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2001 - CT Laboratories - All Rights Reserved
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